The Air Cargo Advance Screening (ACAS) Program went into effect on June 12, 2018, requiring the submission of advanced air cargo information on shipments arriving in the United States from a foreign location. Previously a voluntary process in which many airlines already participated globally, the program requirements are now mandatory for airlines flying to the United States. This is a necessary measure as the Department of Homeland Security (DHS) continues to raise the baseline on aviation security worldwide.

As part of the ACAS program, participating carriers submit a subset of required pre-arrival air cargo data to CBP at the earliest point practicable and prior to loading the cargo onto aircraft destined to or transiting through the United States.